The multidisciplinary research team was organized to devote research efforts in the trans-generational effects of sleep deprivation. There are Four Major Research Aims:

1. To investigate the metabolic dysfunction and the role of Orexin system among offspring mice of maternal early-life sleep deprivation.
2. To investigate the cognitive and psychological impairments among offspring mice of maternal early-life sleep deprivation.
3. To explore the role of epigenetic reprogramming of germ cells as the mechanisms for above changes among offspring mice of maternal early-life sleep deprivation.
4. To verify above findings by using human cohorts in the proximate situation of maternal early-life sleep deprivation.