Research | Departments
Research
Departments
Research highlights of the AMT Lab
Dr. Chen’ main research topic is urological cancers
Email | kuanchou@tmu.edu.tw
Profile | Academic Hub/Pure Experts
Kuan-Chou Chen
Kuan-Chou Chen
Graduate Institute of Clinical Medicine
Professor (Ph.D)
Research Interests
Prostate hyperplasia, prostate cancer, Genitourinary cancer, Urinary indicative surgery in Teaching Hospital Accreditation, Reproductive medicine, General urinary system diseases
Laboratory
Laboratory of Advanced Molecular Therapeutics (AMT Lab)
2023
Cheng LH, Hsu CC, Liao WY, Yang PM, Liao TY, Chan TS, Tsai KK.
ASPM activates Hedgehog and Wnt signaling to promote small cell lung cancer stemness and progression.
Cancer Research 2023;83:830-844 (IF=13.312; corresponding author).
Abstract
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Tsai KK, Bae BI, Hsu CC, Cheng LH, Shaked Y.
Oncogenic ASPM is a regulatory hub of developmental and stemness signaling in cancer.
Cancer Research 2023;83:2993-3000 (IF=13.312; first and corresponding author).
Abstract
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2022
Tsai KK, Huang SS, Northey J, Liao WY, Hsu CC, Cheng LH, Werner M, Chuu CP, Chatterjee C, Lakins, JN, Weaver VM*.
Screening of organoids derived from patients with breast cancer implicates the repressor NCOR2 in cytotoxic stress response and anti-tumor immunity.
Nature Cancer 2022;3:734-752 (IF=23.177; first and co-corresponding author).
Abstract
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2016
Chan TS, Hsu CC, Pai VC, Liao WY, Huang SS, Tan KT, Yen CJ, Hsu SC, Chen WY, Shan YS, Li CR, Lee MT, Jian KY, Chu JM, Lien GS, Weaver VM, Tsai KK.
Metronomic chemotherapy prevents therapy-induced stromal activation and induction of tumor-initiating cells.
Journal of Experimental Medicine 2016;213:2967-2988 (IF=17.579; corresponding author
Abstract
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2013
Wang WY, Hsu CC, Wang TY, Li CR, Hou YC, Chu JM, Lee CT, Liu MS, Su JJ, Jian KY, Huang SS, Jiang SS, Shan YS, Lin PW, Shen YY, Lee MT, Chan TS, Chang CC, Chen CH, Chang IS, Lee YL, Chen LT, Tsai KK.
A gene expression signature of epithelial tubulogenesis and a role for ASPM in pancreatic tumor progression.
Gastroenterology 2013;145:1110-1120 (IF=33.883; corresponding author).
Abstract
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