Research | Departments
Research
Departments
Research | Departments
Research
Departments
Professor
Cell Biology, Toxicology, Nephrology, Cancer Biology, Nanomedicine
Laboratory of Nephrology and Molecular Toxicology
leu3@tmu.edu.tw
Hui-Wen Chiu received her Ph.D. in the Department of Environmental and Occupational Health, College of Medicine from National Cheng Kung University (NCKU) in 2011. Dr. Chiu has been a postdoctoral fellow for three years at NCKU. In 2014, she was employed as an Assistant Professor at Taipei Medical University (TMU). Dr. Chiu is a Professor at the Graduate Institute of Clinical Medicine, College of Medicine, TMU in 2021. Her research topics include nephrology, toxicology, cell biology, and cancer biology. Recently, she focused on studying the effects of microplastics and nanoplastics on human health. Furthermore, she was invited to write a review article about this topic for Nature Reviews Nephrology (IF=41.5, 1/88 in Urology & Nephrology).
Her specialties are nephrology, toxicology, cell biology, and cancer biology. She uses omic data, bioinformatics and high-throughput virtual screening methods to study toxicology, kidney diseases and cancer biology. Recently, the plastic waste matter has been relevant to Sustainable Development Goals (SDGs). She focused on studying the effects of microplastics and nanoplastics on human health. In addition, she devotes the 3Rs alternatives to minimize the number of animals and partially replace the use of animals.
1. Dr. I-Jen Chiu (M.D., Ph.D.)
2. Dr. Cai-Mei Zheng (M.D., Ph.D., Associate Professor)
3. Dr. Wen-Chih Liu (M.D., Ph.D., Assistant Professor)
4. Dr. Jui-Hsiang Lin (M.D., Ph.D.)
5. Dr. Jian-Liang Chou (Postdoctoral fellow)
6. Dr. Yung-Li Wang (Postdoctoral fellow)
7. Dr. Hung-Jin Huang (Postdoctoral fellow)
8. Dr. Li-Ju Ho (M.D., Ph.D. student)
9. Dr. Ruei-Yu Su (M.D., Ph.D. student)
10. Miss Jen-Ning Chang (Research Assistant)
11. Mrs. Yi-Jie Chen (Research Assistant)
12. Mr. Yu-Jhe Chiu (Research Assistant)
13. Miss Tzu-Hsuan Huang (Research Assistant)
1. W-C Liu, H-W Chiu, C-L Chou, Y-J Chiu and Y-H Lee*. Lactoferrin attenuated urban particulate matter-induced nephrotoxicity by regulating the CSF2/CENPE axis. Environmental Pollution 318, 120871 (2023)
2. C-M Zheng, K-C Lu, Y-J Chen, C-Y Li, Y-H Lee* and H-W Chiu*. Matrix metalloproteinase-7 promotes chronic kidney disease progression via the induction of inflammasomes and the suppression of autophagy. Biomedicine & Pharmacotherapy 154, 113565 (2022)
3. Y-L Wang#, Y-H Lee, Y-H Hsu, I-J Chiu, C C-Y Huang, C-C Huang, Z-C Chia, C-P Lee, Y-F Lin# and H-W Chiu*. The kidney-related effects of polystyrene microplastics on human kidney proximal tubular epithelial cells HK-2 and male C57BL/6 mice. Environmental Health Perspectives 129, 57003 (2021)
4. Y-H Hsu#, H-C Chuang, Y-H Lee, Y-F Lin, Y-J Chen, T-C Hsiao, M-Y Wu# and H-W Chiu*. Traffic-related particulate matter exposure induces nephrotoxicity in vitro and in vivo. Free Radical Biology & Medicine 135, 235-244 (2019)
5. Y-F Lin, I-J Chiu, F-Y Cheng, Y-H Lee, Y-J Wang, Y-H Hsu and H-W Chiu*. The role of hypoxia-inducible factor-1α in zinc oxide nanoparticle-induced nephrotoxicity in vitro and in vivo. Particle and Fibre Toxicology. 13(1):52 (2016)